Otrivin

Generic Name: xylometazoline nasal (zye loe me TAH zoe leen)
Brand Names: Otrivin

What is Otrivin (xylometazoline nasal)?

Xylometazoline nasal is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in the body. The nasal formulation acts directly on the blood vessels in the nasal tissues. Constriction of the blood vessels in the nose and sinuses leads to a decrease in congestion.

Xylometazoline nasal is used to treat congestion associated with allergies, hay fever, sinus irritation, and the common cold.

Xylometazoline nasal may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Otrivin (xylometazoline nasal)?


Do not use xylometazoline nasal for longer than 3 to 5 days. Longer use could cause damage to the nasal tissue and lead to chronic congestion. If your symptoms do not improve, see your doctor.

Do not use this medication in larger doses or more often than is recommended. Too much xylometazoline nasal could be harmful. Xylometazoline nasal should not be used more often than two to three times a day (every 8 to 10 hours).
What should I discuss with my healthcare provider before using Otrivin (xylometazoline nasal)?

Do not use xylometazoline nasal if you have taken a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. This could cause a dangerous drug interaction with serious side effects.
Before using this medication, tell your doctor if you have


high blood pressure;

heart disease, hardening of the arteries, or irregular heart beats;

thyroid problems;

diabetes;

glaucoma or increased pressure in the eye;

an enlarged prostate or difficulty urinating;

liver disease; or

kidney disease.

You may not be able to use xylometazoline nasal, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether xylometazoline nasal will be harmful to an unborn baby. Do not use xylometazoline nasal without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether xylometazoline nasal could be harmful to a nursing baby. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.